Increased risk of dying from cardiovascular disease for men with erectile dysfunction and low testosterone

Increased risk of dying from cardiovascular disease for men with erectile dysfunction and low testosterone

Image: Human heart

1 April 2011. Nearly 1700 men attending an andrology clinic for erectile dysfunction were monitored for an average of 4.3 years to find out whether those with low testosterone levels were more likely to suffer a major cardiovascular disease event, such as a heart attack or stroke.

Key Findings

  • At the start of the study, over 22% of the men had testosterone levels in the blood that were lower than the widely accepted lower limit for normal testosterone levels (the medical term for low testosterone is hypogonadism)
  • Over the course of the study, 139 men had a major cardiovascular event, such as heart attack, stroke, sudden cardiac death or other major cardiac events
  • For 15 of these men, the major cardiovascular event was fatal
  • Although having a low testosterone level did not make men more likely to have a cardiovascular event, men with lower levels of testosterone who had a major cardiovascular event were seven times more likely to die than those with higher testosterone levels.

Source: Low testosterone is associated with an increased risk of MACE lethality in subjects with erectile dysfunction. Corona G, Monami M, Boddi V, et al. J Sex Med 2010;7(4 Pt 1):1557-1564.

Background information

There is increasing evidence that erectile dysfunction may be a warning sign of a number of disease conditions, such as high blood pressure, metabolic syndrome, diabetes mellitus, depression and coronary heart disease.

  • This study is important as it is the first to show that low testosterone increases the risk of men with erectile dysfunction dying from cardiovascular events
  • Low testosterone is often a contributing factor to erectile dysfunction
  • Seeking advice or treatment for symptoms of erectile dysfunction gives an opportunity for both the patient and his doctor, as a check-up may uncover other health issues that would benefit from early treatment or lifestyle changes
  • It is known that testosterone replacement therapy benefits sexual function and improves the effectiveness of common treatments for erectile dysfunction in men with low testosterone
  • Testosterone replacement therapy may also have benefits in preventing or slowing the development of atherosclerosis
  • Screening for low testosterone may also be a worthwhile way of discovering those men most at risk from heart disease
  • However, more study is needed to find out if testosterone replacement therapy can help prevent unnecessary deaths from cardiovascular disease in men with erectile dysfunction.
For more information please visit links to the references below

References:

  1. http://www.nebido.com/increased-risk-of-dying-from-cardiovascular-disease-for-men-with-ed-and-low-testosterone
  2. http://onlinelibrary.wiley.com/doi/10.1111/j.1743-6109.2009.01690.x/abstract

About yuan ade sukma, MD

I'm an Indonesian doctor. I Believe that science and knowledge do not belong to anyone in the world. Science and knowledge is meant to be shared to make the world a better place to live. But if you find any material posted here is violating any copyrights, feel free to contact me and I will delete that. I believe that someday my blog can change the world. I BELIEVE in the POWER of WORDS! Do you..?
Gallery | This entry was posted in Andrology Latest Update and tagged , , , . Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s