List of Medications that May Cause Erectile Dysfunction

Medications that can cause erectile dysfunction (ED)

Many commonly prescribed medications can cause erectile dysfunction (ED) in men and female sexual dysfunction in women. If you find a medication that you are currently taking on the list below and it is causing problems with erections, have a talk with your doctor about helping you find a substitute that may be less likely to cause erectile dysfunction.

Antihypertensive (blood pressure medicines):

Associated with decreased libido, decreased arousal and orgasmic disorder in women.

Associated with decreased libido, decreased arousal, orgasmic disorder and erectile dysfunctionin men. High blood pressure medicines and diuretics (“water pills”):

  • Atenolol (Tenormin)
  • Bethanidine
  • Bumetanide (Bumex)
  • Captopril (Capoten)
  • Chlorothiazide (Diuril)
  • Chlorthalidone (Hygroton)
  • Clonidine (Catapres)
  • Enalapril (Vasotec)
  • Furosemide (Lasix)
  • Guanabenz (Wytensin)
  • Guanethidine (Ismelin)
  • Guanfacine (Tenex)
  • Haloperidol (Haldol)
  • Hydralazine (Apresoline)
  • Hydrochlorothiazide (Esidrix)
  • Labetalol (Normodyne)
  • Methyldopa (Aldomet)
  • Metoprolol (Lopressor)
  • Minoxidil (Loniten)
  • Nifedipine (Adalat, Procardia)
  • Phenoxybenzamine (Dibenzyline)
  • Phentolamine (Regitine)
  • Prazosin (Minipress)
  • Propranolol (Inderal)
  • Reserpine (Serpasil)
  • Spironolactone (Aldactone)
  • Triamterene (Maxzide)
  • Verapamil (Calan)

Commonly used medications are:

  • Beta Blockers: Inderal, Lopres- sor, Corgard, Blo- cadren, Tenormin, Toprol
  • Calcium Channel Blockers: Adalat, Procardia, Calan, Isoptin, Verelan, Cardizem, Dilacor XR, Tiazac, Norvask
  • Alpha Blockers: Doxazosin, Prazosin, Terazosin
  • Diuretics: Diuril, Aldactone, Lasix

Medications used to treat depression, anxiety and sedatives:

Associated with erectile dysfunction, orgasmic disorders in men and orgasmic disorders, loss of sexual desire and arousal in women.

Antidepressants and other psychiatric medications commonly used :

  • Amitriptyline (Elavil)
  • Amoxapine (Asendin)
  • Buspirone (Buspar)
  • Chlordiazepoxide (Librium)
  • Chlorpromazine (Thorazine)
  • Clomipramine (Anafranil)
  • Clorazepate (Tranxene)
  • Desipramine (Norpramin)
  • Diazepam (Valium)
  • Doxepin (Sinequan)
  • Fluoxetine (Prozac)
  • Fluphenazine (Prolixin)
  • Imipramine (Tofranil)
  • Isocarboxazid (Marplan)
  • Lorazepam (Ativan)
  • Meprobamate (Equanil)
  • Mesoridazine (Serentil)
  • Nortriptyline (Pamelor)
  • Oxazepam (Serax)
  • Phenelzine (Nardil)
  • Phenytoin (Dilantin)
  • Sertraline (Zoloft)
  • Thioridazine (Mellaril)
  • Thiothixene (Navane)
  • Tranylcypromine (Parnate)
  • Trifluoperazine (Stelazine)

Commonly used medications are:

  • Antidepressants: Prozac, Zoloft, Paxil, Luvox, Serzone, BuSpar, Norpramin, Prolixin, Lithium, Mellaril, Nardil, Serax, Anafranil, Elavil, Tofranil, Sinequan, Pamelor
  • Neuroleptics: Thorazine, Haldol, Zyprexa
  • Sedatives: Librium, Valium, Xanax, Quaalude (methaqualone), barbiturates, Ativan


Associated with lack of lubrication in women leading to dyspareunia. In men, erectile dysfunction and decreased libido.

Commonly used medications are:

  • Cimetidine (Tagamet)
  • Dimenhydrinate (Dramamine)
  • Diphenhydramine (Benadryl)
  • Hydroxyzine (Vistaril)
  • Meclizine (Antivert)
  • Nizatidine (Axid)
  • Promethazine (Phenergan)
  • Ranitidine (Zantac)
  • Dramamine, Benadryl, Vistaril, Antivert, Phenergan

Medication used to treat dyslipidemia:

Associated with erectile dysfunction in men. Commonly used medications are the fibrates such as gemfibrozil and statins, such as simvastatin. For more information click here

  • Fibrates –> gemfibrosil, bezafibrate, fenofibrate, ciprofibrate.
  • Statins –> simvastatin, pravastatin, fluvastatin, atorvastatin, cerivastatin, colestipol, cholestyramine.

Anti-Diabetic Drugs:

Diabetes itself is the main cause of erectile dysfunction. However several reports indicates that using anti-diabetic drugs is associated with ED.

  • Glimepiride (amaryl)

Medication used to treat cancer:

Associated with decreased libido and erectile dysfunction in men and dyspareunia in women. Chemotherapy and hormonal medications:

  • Antiandrogens (Casodex, Flutamide, Nilutamide)
  • Busulfan (Myleran)
  • Cyclophosphamide (Cytoxan)
  • Ketoconazole
  • LHRH agonists (Lupron, Zoladex)

Commonly used medications are:

  • Tamoxifen, Lupron, Flutamide, Nilutamide, Myleran, Cytoxan, Ketoconazole, Zoladex, Casodex

Birth Control:

Associated with decreased libido, arousal disorder and vaginal dryness in women.

Commonly used medications are:

  • Ortho 7/7/7, Tricyclen, Cyclen, Depo Provera

Anti Parkinson’s:

Associated with erectile dysfunction and increased libido in men and women. Parkinson’s disease medications:

  • Benztropine (Cogentin)
  • Biperiden (Akineton)
  • Bromocriptine (Parlodel)
  • Levodopa (Sinemet)
  • Procyclidine (Kemadrin)
  • Trihexyphenidyl (Artane)

Commonly used medications are:

  • Cogentin, Akineton, Parlodel, Sinemet, Kemadrin, Artane

Non-steroidal Anti Inflammatory:

Associated with decreased lubrication in women and erectile dysfunction in men.

Commonly used medications are:

  • Naproxen (Anaprox, Naprelan, Naprosyn)
  • Indomethacin (Indocin)
  • lbuprofen

Opiate Analgesics (painkillers)

  • Codeine
  • Fentanyl (Innovar)
  • Hydromorphone (Dilaudid)
  • Meperidine (Demerol)
  • Methadone
  • Morphine
  • Oxycodone (Oxycontin, Percodan)

Other medications:

Associated with various sexual disorders. Other medications:

  • Aminocaproic acid (Amicar)
  • Atropine
  • Clofibrate (Atromid-S)
  • Cyclobenzaprine (Flexeril)
  • Cyproterone
  • Digoxin (Lanoxin)
  • Disopyramide (Norpace)
  • Estrogen
  • Finasteride (Propecia, Proscar, Avodart)
  • Furazolidone (Furoxone)
  • H2 blockers (Tagamet, Zantac, Pepcid)
  • Indomethacin (Indocin)
  • Lipid-lowering agents
  • Licorice
  • Metoclopramide (Reglan)
  • NSAIDs (Ibuprofen, etc.)
  • Orphenadrine (Norflex)
  • Prochlorperazine (Compazine)
  • Pseudoephedrine (Sudafed)

Commonly used medications are:

  • Amicar, Atropine, Compazine. Flexeril, Lanoxin, Norpace, Proscar, Propecia

Non Prescription/ Illegal Drugs:

Alcohol can cause decreased libido in men and women as well as orgasmic disorders and erectile dysfunction in men.

Heroin and morphine can cause decreased libido in men and women and can cause ejaculatory disorders in men.

Over time, amphetamines and cocaine can cause erectile dysfunction in men. Marijuana can cause vaginal dryness in women.


DO NOT stop your medication before you consult your doctor. If you think you got ED from the medications you’re taking, you better talk to your doctor and your doctor may give you another prescription which is safer for your sexual health.

If you do have experience about ED yourself and if you thought it’s caused by the medication you are taking please share it with us.



About yuan ade sukma, MD

I'm an Indonesian doctor. I Believe that science and knowledge do not belong to anyone in the world. Science and knowledge is meant to be shared to make the world a better place to live. But if you find any material posted here is violating any copyrights, feel free to contact me and I will delete that. I believe that someday my blog can change the world. I BELIEVE in the POWER of WORDS! Do you..?
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3 Responses to List of Medications that May Cause Erectile Dysfunction

  1. george john says:

    name the safer drugs in a patient with with Hypertension and hypercholesterolemia who face problem of ED also

    • Anti hypertensive which is considered save is angiotensin II type 1 receptor (AT1) antagonists, such as losartan, and valsartan, dont forget to do low salt and low fat diet. for anti cholestrol the best med is low fat diet and exercises

  2. Elvin Comrey says:

    If you are concerned about your blood pressure there are different types of medication you can take to help control or lower your pressure. You might try some lifestyle changes first before opting for medicine. Remember that sometimes medicine is the only way you might be able to lower it. Different lifestyle changes do not always work on their own. First you might consider your diet. Do you consider yourself a healthy eater? Do you think you have a pretty healthy diet? Your diet could be affecting your blood pressure. High amounts of salt and sodium intake can raise your blood pressure. Try to limit your salt intake and eat more fresh fruits and vegetables. If you love salt, consider substituting it with a different seasoning. There are so many different kinds of seasonings available you can easily find something to your liking…

    Our blog

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